![]() ![]() It can cause vitamin especially B12 deficiency and iron deficiency anaemia. Indeed, many people with "IBS" may well have SIBO. Other symptoms can include alternating loose stools and sometimes constipation and flatulence. There can be associated abdominal discomfort with belching which can cause reflux of stomach contents and cause or exacerbate reflux symptoms. Commonly people will experience bloating after eating especially carbohydrates as very often the bacteria in the gut ferment these into gases. SIBO can cause an enormously wide and variable set of symptoms. ![]() Abnormal connections between areas of the gut called fistulae.It's thought bacteria can "hide" in blind pouches. In patients who have undergone gut surgery with for instance removal of the ileo-caecal valve during colon cancer resection. So, these drugs may well be one of the most common causes of a change in the normal gut Biome and the consequences of this. At RefluxUK we have recently completed a study that showed that nearly 2/3 of patients with reflux and SIBO symptoms and taking PPIs long-term tested positive for SIBO. Pylori infection but the most common cause of profound acid production depression are the powerful anti-acid medications Proton Pump Inhibitors (PPIs). Low stomach acid can occur following surgery and with h. Stomach acid is produced normally for a number of reasons, one of which is to help sterilise the food we eat. This can be caused by connective tissue conditions such as scleroderma, nervous system disease such as Parkinson's, hypothyroidism but probably most commonly diabetes as this can cause damage nerves supplying the gut. Poor gut motility which prevents the normal "clearing" of bacteria.There are thought to be many reasons why SIBO develops but the most likely are:
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